Origin and Habitat: Tropical areas of southern Mexico (México, Michoacán, Morelos, Oaxaca), but now largely spread around Mexico.

• Peniocereus serpentinus var. ambiguus (Bonpl.)
• Cactus ambiguus Bonpl.
• Cereus ambiguus (Bonpl.) Bonpl.
• Nyctocereus serpentinus var. ambiguus (Bonpl.) Borg

• Peniocereus serpentinus (Lag. & Rodr.) N.P.Taylor
• Cactus serpentinus Lag. & Rodr.
• Cereus ambiguus strictior Weing.
• Cereus splendens Hort.Angl. ex Salm-Dyck
• Echinocereus serpentinus (Lag. & Rodr.) Lem.
• Nyctocereus serpentinus (Lag. & Rodr.) Britton & Rose
• Peniocereus castellanosii (Scheinvar) Scheinvar
• Nyctocereus castellanosii Scheinvar
• Peniocereus kalbreyerianus (Wercklé)
• Cereus kalbreyerianus Wercklé
• Nyctocereus kalbreyerianus (Wercklé) Croizat
• Peniocereus serpentinus var. ambiguus (Bonpl.)
• Cactus ambiguus Bonpl.
• Cereus ambiguus (Bonpl.) Bonpl.
• Nyctocereus serpentinus var. ambiguus (Bonpl.) Borg
• Peniocereus serpentinus var. stellatus (Lem.)
• Cereus serpentinus stellatus Lem.
• Peniocereus serpentinus var. strictior (Walp.)
• Cereus serpentinus strictior Walp.

• Peniocereus serpentinus f. cristata
• Nyctocereus serpentinus f. cristata

Description: It is a fast-growing slender, shrubby columnar cacti from that grows often in groups, erect at first sometimes climbing then leaning and sprawling all over and best tied to something so it wont fall and grow decumbent. It would be good for hanging baskets.
Stem: Slender, snake-like, dark coloured, cylindrical, 3-6 meters long, 2,5-5 cm in diameter.
Roots: Large tuberose
Ribs: 10-17 obtuse.
Areoles: Whitish white wool
Spines: 9 to 14 needle-like spines, whitish to reddish when young, with darker tips, 10-30mm long.
Flowers: When old enough it bears large, nocturnal flowers, they are funnelform, white with pinkish outside segments, 15 to 20cm long (15 cm in diameter), pericarpel and flowers with bristles. The flowers are very fragrant, like gardenias.
Fruits: 4-6 cm long, red, egg-shaped, edible, spiny, with spines that fall when it is ripe.
Seeds: Black 5 mm Long.

Cultivation and Propagation: Produces best results in loose and very drained soil, rich in leaf-mould, and if sufficient water is supplied in warm weather a rather considerable growth can be made. It needs bright shade to partial sun. The plants will stand but little cold and require a minimum winter temperature of about 10° C. (but can resist for short period to 0° C). Growth is rapid, and supports are needed for the stems. The half‑erect habit of the moderately tall plants makes them desirable for middle foreground position in landscap­ing, while the comparatively small room needed for potted plants makes it an acceptable group for greenhouse culture.
Propagation: By grafting or (sometime) by cuttings.
Uses:
- In Mexico it is one of the most widely cultivated species for the beauty of its white flowers that open at night
- Grown in Mexico (Sonora), California and Chile for its fruit.
- Sometime used as a strong and fast growing grafting stock.